Germ cell biology and developmental programming in epigenetic inheritance of diseases – Qiaolin Deng's research group

Germ Cell Biology and Developmental Programming

Reproduction is a fundamental process for passing traits from parents to offspring, traditionally believed to occur only through germline genetic modifications.

However, evidence shows that early-life environmental exposures, influenced by parental health and developmental programming, can permanently impact offspring's health and disease risk.

My lab studies how these interconnected processes, broadly termed as nature and nurture, shape the health trajectory of offspring.

Our research group is interested in the developmental principles of germline specification in health and disease using mouse models and human stem cell cultures coupled with state-of-the-art molecular and cellular tools.

Author's summary: Researching germ cell biology and developmental programming.

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ki.se ki.se — 2025-10-12